She'd destroy Santana (way too small for her) and probably dominate Sarah as well. I know Sarah is strong and a good grappler who will go after her huge tits, but Chakira is not only big/strong but she has the skill and mean streak to steamroll opponents smaller than her.
I think Alexa could keep up with her when standing, she did so against the bigger Davina, but if the fight goes to the ground, it would be over for her. Alexa had issues with Paris while on the ground and Paris doesn't even have a mean streak, plus is much leaner than Chakira. The only other SuiteFights opponent that could possibly give her a good fight might be Bella Luxx. Bella looked vicious at times against Nikki and she definitely looks like someone that has plenty of experience fighting in real life. I think she had Nikki beat, but Steve did his usual thing of being over protective of a fighter he likes and didn't want to see Nikki lose, even though Bella had a clear submission early in that fight. Another opponent I'd be interested in would be ECNWC Brooke because she has a military background and has beaten men in real life (from what I've heard) while claiming she went easy on the girls at SuiteFights because she wanted the matches to last longer. Put her up against Chakira and that excuse goes out the window.